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Effect of Early Treatment with Ivermectin
among Patients with Covid-19

Original Article

Posted By: IowaDad, 5/7/2022 11:15:13 AM

The efficacy of ivermectin in preventing hospitalization [SNIP] is unclear. We conducted a double-blind, randomized, placebo-controlled, adaptive platform trial involving symptomatic SARS-CoV-2–positive adults. A total of 3515 patients were randomly assigned to receive ivermectin (679 patients), placebo (679), or another intervention (2157). Treatment with ivermectin did not result in a lower incidence of medical admission to a hospital due to progression of Covid-19.

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Reply 1 - Posted by: seamusm 5/7/2022 11:23:58 AM (No. 1149130)
I wish I could trust these results without hesitation - but my medical colleagues have whored themselves so much over the last few years that I will wait to see confirmatory data. Even so, I am left wondering what works if anything and grateful that Nature is ending the pandemic as she has always done.
45 people like this.

Reply 2 - Posted by: rockeysroomie 5/7/2022 11:31:48 AM (No. 1149137)
What #1 said.
22 people like this.

Reply 3 - Posted by: skymom 5/7/2022 11:33:20 AM (No. 1149139)
This study doesn't test the FLCCC protocol (shorter duration of Ivermectin use - only 1 to 3 days, vs 5 or until recovered for FLCCC. Also, they include people who have had COVID symptoms for up to 7 days - not exactly early intervention. But rest assured, this will be the study that gets touted by establishment media and healthcare. Why didn't they actually test a protocol that is being used and has had demonstrated effectiveness (e.g. FLCCC, Dr Z, Drs. Tyson and Fareed)? They either give lethal doses (as was the case for one HCQ study) or weak dosages... I can't trust these people any further than I can throw them.
42 people like this.

Reply 4 - Posted by: Marzipan4 5/7/2022 11:38:29 AM (No. 1149141)
Dear Iowa, I am so glad you posted this article for this is the reason why ivermectin is panned and poo-pooed away. Ivermectin is effected As An Early Treatment within the first days as Drs Immanuel, McCullough and 17,000 worldwide professionals have shouted from the rooftops. Dr. Zelenco has a protocol treatment with an 98% efficacy if started within the first days of symptoms, FTA”… We conducted a double-blind, randomized, placebo-controlled, adaptive platform trial involving symptomatic SARS-CoV-2–positive adults recruited from 12 public health clinics in Brazil. Patients who had had symptoms of Covid-19 for up to 7 days and had at least one risk factor for disease progression were randomly assigned to receive ivermectin (400 μg per kilogram of body weight) once daily for 3 days or placebo. (The trial also involved other interventions that are not reported here.)””. If you have had Covid 7 days means you are either recovering or heading to the hospital. Please repeat after me, personal choice, early intervention by a medical professional, not a Pharma rep.
40 people like this.

Reply 5 - Posted by: MindMadeUp 5/7/2022 11:53:56 AM (No. 1149156)
This study was conducted without administering zinc along with the ivermectin. It's a little like handing people guns with no bullets and then announcing the guns proved to be useless in self-defense.
41 people like this.

Reply 6 - Posted by: DVC 5/7/2022 11:55:51 AM (No. 1149158)
Hogwash.
19 people like this.

Reply 7 - Posted by: DVC 5/7/2022 11:56:49 AM (No. 1149161)
Clarification.....Pfizer funded, hogwash.
27 people like this.

Reply 8 - Posted by: earlybird 5/7/2022 12:00:03 PM (No. 1149164)
Many of us have heard of this study, which ended up in what amounts to a scientific question mark. The other interventions were not identified (why?) and it appears that the treatment with ivermectin began too late. The subjects were already in an acute state. It wouldn’t surprise me if I found out that Iowa Dad was somehow affiliated with one of the pharmaceutical houses involved in making the vaccines or perhaps one of the pricey “interventions” that have been found to have some serious side effects/adverse reactions. He clearly has more than a personal opinion. He is obsessive. Trying to change minds. An agenda. I first heard of ivermectin when Dr. Lee Merritt, in videos made early in the Covid siege, named ivermectin as one item she had in her personal Covid Kit.
26 people like this.

Reply 9 - Posted by: Mofongo 5/7/2022 12:23:56 PM (No. 1149193)
Sheesh, it’s NEJM. Get a Ludlum novel. Much better fiction. I knew it was going to be the father of some long-suffering kid in Iowa.
13 people like this.

Reply 10 - Posted by: DVC 5/7/2022 12:33:51 PM (No. 1149204)
I agree with #8, this OP seems very likely to have a financial interest in this matter.
14 people like this.

Reply 11 - Posted by: lakerman1 5/7/2022 12:43:18 PM (No. 1149210)
I believe the protocol for the use of Ivermectin to teat Kung Flu includes the administration of Zinc along with a Zithromax (Z pack.) The Ivermectin attacks the protein coating of the Kung Flu virus, thus allowing the zithromax to penetrate and kill the virus. I read the offering of the Iowa Dude as carefully as possible, and in the Brazil research, no mention is made of the Z pack nor the Zinc. In addition, the treatment protocol is recommended to be used at the first symptom of Kung Flu. Waiting for up to 7 days may be too late. Think of the treatment protocol for a cold sore. You are to app[y the medication immediately, to diminish the lesion .
14 people like this.

Reply 12 - Posted by: DVC 5/7/2022 12:46:40 PM (No. 1149211)
My study of early ivermectin use has two phases. Phase One was last August when 220,000,000 people in Uttar Pradesh used it to get their death rate from the Wuhan virus down to nearly zero after they used it for six weeks. And it stayed there, in a third world environment which has notably limited health care resources, but handed out ivermectin kits to everyone infected, and used it prophylactically to prevent their traveling medical teams from getting infected. They had below a 5% vaccination rate in the province. And my Phase Two trials are just concluding.....three close friends who got the virus, two with the ineffective mRNA shots and one without. Each started ivermectin and the FLCCC treatments within a couple of days of first symptoms, and two were feeling much better 24 hours after taking the first ivermectin, and one of the "vaccinated" ones was still running a 101F fever for two days, finally broke on the third day, symptoms rapidly tailing off, but still a bit weakened for a few more days. Ivermectin works, the mRNA shots protect not at all from infection, and reduced symptoms.....not at all. I am becoming convinced that the "reduced symptoms" claim, which is about the final straw that they grasp at, is also as bogus as the other two claims - "you'll be protected" (false) and "you won't pass it on" (false). And this doesn't even touch the huge numbers of people who these shots killed or maimed, and whose immune systems are likely to have long term damage.
18 people like this.

Reply 13 - Posted by: paral04 5/7/2022 12:59:40 PM (No. 1149218)
The problem with this study is that they waited 7 days after a patient tested positive to administer the Ivermectin treatment. Why wait that long? Did they not study the results if the patient were administered Ivermectin immediately after testing positive for Covid? Holding back on treatment is criminal and a cute way to skew treatment results.
16 people like this.

Reply 14 - Posted by: Venturer 5/7/2022 1:08:46 PM (No. 1149227)
They waited far too long to take this test and then they screwed it up.
12 people like this.

Reply 15 - Posted by: kono 5/7/2022 1:12:48 PM (No. 1149232)
FTA: "we report here on the use of ivermectin at a dose of 400 μg per kilogram of body weight for 3 days as compared with placebo." 3 days? I was advised to use for at least 5. But I wound up stopping after 4, because all my covid symptoms subsided to nearly zero by then. My treatment also included Quercetin, and I made no effort to experiment with alternative combinations, placebos, et al - just took a dose of each daily for four days. And the results for me were better than for a housemate who came down with covid the same week and had the same treatment but for 5 days, whose symptoms were more numerous, more pronounced, and longer-lasting. (He claims he still can't taste much of anything, while I noticed no taste-related symptoms for even a day.) It's pretty clear that the effects of infection vary from case to case, as do the effects of treatments.
9 people like this.

Reply 16 - Posted by: Kafka2 5/7/2022 1:16:25 PM (No. 1149237)
There is nothing surprising that treatment with ivermectin did not result in a lower incidence of medical admission to a hospital due to progression of Covid-19. Ivermectin was never claimed to prevent Covid-19. The only claim was that it reduce the severity of Covid-19 symptoms and gave the patient a better chance of survival and full recovery. Since medical admission to a hospital would occur before the first treatment with ivermectin, it is logical that ivermectin would not and could not result in a lower incidence of medical admission to a hospital. FTA: "Patients who had had symptoms of Covid-19 for up to 7 days and had at least one risk factor for disease progression were randomly assigned to receive ivermectin (400 μg per kilogram of body weight) once daily for 3 days or placebo." Two observations: First, ivermectin needs to be give early. After, 7 days Covid has done major damage. ivermectin is to slow the damage giving the body a fighting chance. Its effectiveness is reduce by delay. Second: Risk factors are a wild card. The patients had one (or more) risk factor(s). Both the severity of specific risk factors and their number can vary greatly. By selectively assigning patients to ivermectin or placebo groups, one could make the placebo look more effective. But, you can decide for yourself the validity of this study.
5 people like this.

Reply 17 - Posted by: udanja99 5/7/2022 1:17:49 PM (No. 1149240)
After I read the headline and the source of the article, I looked at who had posted it. I didn’t bother to read any further.
16 people like this.

Reply 18 - Posted by: Jesuslover54 5/7/2022 1:47:09 PM (No. 1149269)
What was the "other intervention" that took the majority of the patients? Besides I think IowaDad lives in Brooklyn.
5 people like this.

Reply 19 - Posted by: ussjimmycarter 5/7/2022 1:51:29 PM (No. 1149274)
TRUMP SAID TO DRINK BLEACH…CAUSE…RACIST!!! Liberal freak out for today!
4 people like this.

Reply 20 - Posted by: edgar 5/7/2022 1:52:12 PM (No. 1149276)
So, are they saying it is it more effective than getting the jab?
4 people like this.

Reply 21 - Posted by: Norway 5/7/2022 2:21:33 PM (No. 1149296)
It's only unclear to the NEJM.
2 people like this.

Reply 22 - Posted by: JackBurton 5/7/2022 2:39:07 PM (No. 1149312)
OK. This is ONE test. But why cherry pick? This link will give you a summary of results for ONE HUNDRED FIFTY EIGHT trials. (Spoiler: Ivermectin works.) https://c19ivermectin.com/
5 people like this.

Reply 23 - Posted by: Proud Texan 5/7/2022 2:47:21 PM (No. 1149317)
I like several other commenters notice that these researchers are very, very careful not to use the ivermectin along with the rest of the protocol involving zinc in particular, along with vitamin D3 and antibiotics once the patient started having problems. As I understand it, the ivermectin was mostly an enabler for zinc to do the virus destruction. One without the other was just like another posted, a gun without a bullet.
8 people like this.

Reply 24 - Posted by: earlybird 5/7/2022 3:04:26 PM (No. 1149327)
This study was paid for (at least in part( by the Rainwater Charitable Foundation. I knew Richard Rainwater in the 80s. A high-flying investor who made megabucks for himself and also for the Bass Brothers of Texas. He had to have included Big Pharma in his portfolios. Then he ended up with a severe neurological condition that eventually took his life. Most of his fortune went to his foundation which was to finance the exploration of neurological conditions like his and to come up with new “modern” treatments. We know who does that. So Rainwater was a Big Pharma guy - even in death - for reasons financial and personal. It is unlikely that his Foundation would be interested in anything but “modern” interventions for any disease.
4 people like this.

Reply 25 - Posted by: earlybird 5/7/2022 3:09:53 PM (No. 1149329)
The object of a study like this is not to verify the efficacy of an existing drug that, used properly with other existing drugs and supplements, had actually shown that it worked. In real people in real life, not a carefully orchestrated “trial”. It was important to the researchers to neutralize the buzz about ivermectin, even though they could not completely write it off. Thus the word “unclear”.
4 people like this.

Reply 26 - Posted by: 901AtTheRiver 5/7/2022 3:44:58 PM (No. 1149354)
Failure to test known effective protocol means the "study" is worthless.
6 people like this.

Reply 27 - Posted by: DVC 5/7/2022 4:32:23 PM (No. 1149368)
The lie is that starting ivermectin after 7 days is called "early treatment". NO, that is "too late treatment". Intentionally too late? Probably so. And as others have pointed out - NOT the FLCCC protocol which is not just ivermectin, and to reiterate - TOO LATE to do any good.
7 people like this.

Reply 28 - Posted by: bogeegolf 5/7/2022 5:25:25 PM (No. 1149383)
That reminds me my sister owes me some ivermectin.
3 people like this.

Reply 29 - Posted by: mamabear 5/7/2022 7:30:35 PM (No. 1149430)
Second time this article (or one like it) was posted by the same person. He just keeps walking into the wrong bar... :-)
5 people like this.

Reply 30 - Posted by: Kumoan 5/7/2022 8:18:36 PM (No. 1149476)
Google Ivermectin and Chemotherapy for a shock!
4 people like this.

Reply 31 - Posted by: Aeneid1 5/7/2022 9:15:16 PM (No. 1149498)
Because Ivermectin by itself isn’t what people who have success with it take. D3K2 with Zinc and quercetin have shown very positive results. Zelensky Protocol is what is needed early on.
3 people like this.

Reply 32 - Posted by: MickTurn 5/8/2022 10:49:07 AM (No. 1149895)
Results were rigged. In India they had a state/province that was in really bad shape from Covid, they started Ivermectin and it reversed, knocked out Covid in a large majority of patients...
0 people like this.

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