Cancer ´vaccine´ shows promise in human trial of lymphoma patients
CNBC U.S.,
by
Angelica LaVito
Original Article
Posted By: JoElla Bee,
4/8/2019 2:33:32 PM
An experimental cancer "vaccine" showed promising results in a small clinical trial of patients with lymphoma, according to a study published Monday in the journal Nature Medicine.Researchers at New York´s Mount Sinai Hospital tested the treatment in 11 patients with lymphoma. Their results were successful enough to warrant another clinical trial in March on lymphoma patients as well as breast and head-and-neck cancer.Researchers said some patients in the initial human trial went into full remission for months or even years.
Reply 1 - Posted by:
Knotwyrkin 4/8/2019 3:06:42 PM (No. 27388)
I Am Legend.
8 people like this.
Reply 2 - Posted by:
dman 4/8/2019 3:57:20 PM (No. 27387)
Promising, but these breakthroughs are typically years from practicality. Some will eventually pan out, but we must be patient and our optimism cautious until then.
8 people like this.
Reply 3 - Posted by:
DVC 4/8/2019 4:20:57 PM (No. 27384)
I have discussed "the cure for cancer" with my cellular biology research professor old friend many times.
The ultimate answer is some variation on "teaching the immune system to find cancer cells".
This is the root problem: Cancer occurs very frequently in humans, perhaps weekly or even more often in individual cells. But, a person with a normal immune system destroys this one or a few cells of cancer immediately, and no harm is done,you never have any clue that you "had cancer". The harmful cancers are ones which have worked out some camouflage trick so that the immune system cannot identify them and destroy them.
Getting past this camouflage, and teaching the immune system to see the cancer cells is THE ultimate solution.
This sort of ´vaccine´ approach seems reasonable, since the purpose of a vaccine is to pre-train the immune system to identify a pathogen so that it can be destroyed very early, rather than the immune system playing
´catch up´ for the actual disease, and often overwhelmed by reacting too slowly.
Sound strategy, hope it works in practice.
15 people like this.
Reply 4 - Posted by:
Jethro bo 4/8/2019 4:25:26 PM (No. 27381)
Finally something that may stop the spread of malignant progressive, liberal, socialist, fascist Democrat disease.
6 people like this.
Reply 5 - Posted by:
Catherine 4/8/2019 7:24:11 PM (No. 27389)
Okay, big dunce here, but if moles, warts, etc., can be frozen off, why can´t tumors be frozen and removed?
6 people like this.
Reply 6 - Posted by:
DVC 4/8/2019 7:33:04 PM (No. 27379)
They can be excised if compact an contained. The real problem with cancer is when it has "metastasized", or released cancer cells into the lymph system, or blood stream, and sent these cells all through the body to start additional cancers elsewhere.
This is why when cancer is "caught early", it can often be cured very well.
9 people like this.
Reply 7 - Posted by:
DVC 4/8/2019 7:37:32 PM (No. 27380)
"compact and contained".
A friend had an unusual form of pancreatic cancer. It was wrapped into several organs, liver, gall bladder, and wrapped around important nerves and blood vessels.
His brother, a neurosurgeon, warned him that the surgical method was essentially impossible without excising critical tissues accidentally, and missing cancerous tissues. The literal quote from the literal brain surgeon brother was, "imagine trying to sort through wads of wet toilet paper and figure out exactly which layer is bad and which is good". He said that the tissues were visually essentially indistinguishable. If you care, look up Whipple Procedure.
Like trying to sort BBs with a backhoe.
7 people like this.
Reply 8 - Posted by:
chance_232 4/8/2019 8:15:04 PM (No. 27382)
I imagine the vaccine will be jaw dropping stupendously expensive and not covered by most insurance.
Cancer is big big big business. I personally racked up $300,000 in Chemo bills. The drugs/poisons are unbelievably expensive and cancer treatment employes tens of thousands maybe hundreds of thousands.
I would like to believe that a "cure" will come to market and be affordable. The pessimist in me says that this drug will go the way of the 75mpg engine.
7 people like this.
Reply 9 - Posted by:
DVC 4/8/2019 8:42:45 PM (No. 27385)
#9, you can buy a 71 mpg auto today in Europe. Look at a VW Polo small car with a turbodiesel, only sold in Europe. Officially rated in highway cruising at 71 mpg by UK government. Americans are uninterested, so that class of car is not marketed here. When I was in France a couple of years ago, it cost ~$9 per gallon of diesel, it makes sense to some, there.
https://motoreu.com/volkswagen-polo-1.0-tsi-mpg-fuel-consumption-technical-specifications-167133
As to the "200mpg carburetor" stories, claiming to make an ordinary full sized American sedan get ´200mpg´ or ´75 mpg´, they are pure, unadulterated BS. The laws of physics are very clear to a trained engineer, and while we CAN do some pretty good things, it requires special techniques, and small, light weigh, less comfortable cars.
Current best VW US model gets 42 mpg highway, EPA number. For 10K miles per year, $3.60/gal of diesel, 42 mpg = $857/yr fuel cost. 71 mpg = $507/yr fuel cost. Very few Americans would buy a small VW Polo to save $29/month in fuel bills over a much nicer, much larger, much higher performance VW Jetta TDI. Just nobody cares to pinch pennies that hard here. VW knows this and doesn´t even bother to import it.
6 people like this.
Reply 10 - Posted by:
Heraclitus 4/9/2019 12:09:54 AM (No. 27378)
We were hoping and praying that an effective anti-cancer weapon could have been found before my beloved brother lost his battle against vicious cancer.
A course of immunotherapy drugs, well-tolerated, held the cancer at bay for about a year.
We pray for those who will end up in a struggle with cancer, and for the researchers to please work faster... faster.
9 people like this.
Reply 11 - Posted by:
DVC 4/9/2019 3:25:22 AM (No. 27386)
#11, I lost my 35 year friend, mentioned above, about tw years back. Another friend´s 32 year old daughter, an MD, has come up with cancer. So far, treatments are containing it, but who knows how long she will have, or if one of the new therapies will work.
Sorry to year about your brother. This is a terrible disease.
6 people like this.
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Wonderful news!