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For all their risks, opioids had no pain-relieving
advantage in a yearlong clinical trial

Los Angeles Times, by Karen Kaplan

Original Article

Posted By:MissMolly, 3/7/2018 5:01:11 AM

For years, doctors turned to opioid painkillers as a first-line treatment for chronic back pain and aches in the joints. Even as the dangers of addiction and overdoses became more clear, the drugs´ pain-relieving benefits were still thought to justify their risks. Now researchers have hard data that challenges this view. In the first randomized clinical trial to make a head-to-head comparison between opioids and other kinds of pain medications, patients who took opioids fared no better over the long term than patients who used safer alternatives. "There was no significant difference in pain-related function between the 2 groups over

      


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Reply 1 - Posted by: lakerman1, 3/7/2018 5:48:17 AM     (No. 11564497)

The writers chose to collapse two sets of data into one sentence.
First, 115 deaths per day is almost completely
caused by junkies injecting heroin boosted with fentanyl.
Second, we don´t know what a 4 fold increase in hydrocodone means, since the writers cleverly failed to include the numbers.
(If one person died from an rx drug overdose, and next year, 4 people die from ex overdose, that is a fourfold increase.e.
The article is fundamentally dishonest. But, hey! Everyone is writing dishonest articles about opiods.

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Reply 2 - Posted by: gijohn, 3/7/2018 5:57:42 AM     (No. 11564500)

I didn´t see what the trial was using as opioid med. Kind of dishonest if they were prescribing hydrocodone with acetaminophen. I was given acetaminophen after bypass surgery one time and it worked well. I think it was when they were still getting my BP under control. The trouble with those meds is of course the effect on the liver.

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.New_S.
  


 
Reply 3 - Posted by: paperpuncher, 3/7/2018 6:49:48 AM     (No. 11564530)

I´m sorry but, there is a significant difference between surgical pain and "back and joint pain". After major back surgery it is not jut take two Tylenol and call me in the morning.

I certainly can´t see a medic giving Tylenol rather than morphine to a wounded soldier in the field.

The problem with the addictions is the meds are used too often and prescribed to too long a period of time for relatively minor pain.

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Reply 4 - Posted by: Udanja99, 3/7/2018 6:55:49 AM     (No. 11564533)

Acetaminophen is just Tylenol. Hydorcodone is the opioid and, according to my orthopedic surgeon, contains synthetic codein.

I beg to differ on the advantages. If you’ve ever had bone surgery or an abcessed tooth in need of a root canal, you know that opioids are the only thing that really stops the pain. I have had numerous surgeries and there have been moments when I thanked God for oxycodone.

The key is to use them as prescribed and to stop using them as soon as possible. I do find that doctors tend to prescribe more pills than you need. I was once given 30 oxycodone for an abcessed tooth when I had a root canal scheduled 2 days later. Eight pills would have been enough.


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Reply 5 - Posted by: Truthfetish, 3/7/2018 6:57:30 AM     (No. 11564535)

#1, half those junkies got on heroin because they can´t get oxy scripts renewed by that doctor who prescribed them to keep his own NPS numbers high enuf for Obamacare beancounters.

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Reply 6 - Posted by: earlybird, 3/7/2018 6:59:49 AM     (No. 11564537)

I am among those who cannot take opioids because of their side effects. Faced with a fractured pelvis a few years ago, I tried my regular Aleve and it dealt with the pain very successfully. The doctor gave me the option of taking it a little more often than the usual 12 hour intervals specified on the label. As needed. As soon as I didn’t need so much, I tapered it off.

Pain and painkilling are very individual matters, IMO. I can’t see how one opinion on can fit all.

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Reply 7 - Posted by: GO3, 3/7/2018 7:05:36 AM     (No. 11564542)

I too needed something stronger than tylenol after major surgery. However, I think there is a difference between pain relieving and a drug which makes you not care about the pain. Maybe that´s what they are talking about.

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R-TA-Wide_2
  


 
Reply 8 - Posted by: crunchycon, 3/7/2018 7:07:32 AM     (No. 11564544)

Came here to agree with #4. Like others here I have had surgery. I took my pain meds exactly as prescribed and transitioned off at the end of my prescription. I did, of course, experience some pain, particularly during the last hour before the next dose, but II managed it like a tough gal.. Everyone’s story is difficult fly, but my method kept me outof trouble and may work for otherwise.

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Reply 9 - Posted by: citizen, 3/7/2018 7:41:08 AM     (No. 11564581)

Doctors aren´t John Kerry and cannot feel your pain..the pain scale of 1-10 is a useless way to determine an individual´s pain Also this study was done by the VA? Yikes.


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Reply 10 - Posted by: ladydawgfan, 3/7/2018 7:53:10 AM     (No. 11564601)

I am not supposed to take narcotics due to side effects and the fact that they cause my migraines to go out of control. However, I also have a knee that is severely damaged from a fall and because I am a fluffy woman, I cannot find an orthopedist to correct it surgically. Instead, they keep hitting it with cortisone shots and the latest which was Supartz, none of which did any good (although the Supartz did give me some LOVELY migraines!).

The prescription that I am on for pain is a mild narcotic called transfer, which has been in the news lately for other things as well. It controls the pain in my knee and allows me to function. However, it also aggravates my migraines, makes me tired and occasionally gives me double vision. The sooner I am rid of it, the better.

Now if I could just find someone to really listen to me about my knee....

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Reply 11 - Posted by: ladydawgfan, 3/7/2018 7:54:55 AM     (No. 11564604)

*tramadol

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Reply 12 - Posted by: Rather Read, 3/7/2018 7:59:31 AM     (No. 11564615)

I´ve been given opioids after two operations and a wisdom tooth extraction. They never really relieved pain, but I didn´t care that I hurt. I ditched them after two days and went on ibuprophen and that actually relieved the pain.

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.LockDme.


 
Reply 13 - Posted by: greggojo, 3/7/2018 8:11:31 AM     (No. 11564636)

For those concerned about the LATimes cookies:

http://www.post-gazette.com/news/overdosed/2018/03/06/For-all-their-risks-opioids-had-no-pain-relieving-advantage-in-a-yearlong-clinical-trial/stories/201803060191

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Reply 14 - Posted by: Nevadadad46, 3/7/2018 8:30:24 AM     (No. 11564668)

My surgery and pain meds experience proves there can be no substitute for the proper (I said Proper!) dosage of opioids. Wow! You can go from absolute agony to instant nirvana with the right dosage. But, an emergency operation is over in hours, a few days of pain relief and you are on your way home with a hand full of pills to get you through. Then stop it. That process is a "Repeat as often as needed". But, then long term use on a maintenance prescription of opioids (Oxy and hydro)for control of background pain is off the charts insane. If your pain is that bad, you needs much more than the max legal dose (usually 20 mg) of that stuff. Because in almost no time, a month or two, the "maintenance" dose is useless, and your pain is back but you take the damn pills because now stopping them is not an option! And the bad part is, ask for help getting off them from your insurance and they will tell you real quick- "Not part of the plan, baby!" I had to go cold turkey- What a nightmare! Later Wife did, too. And she had a much rougher time of it. No help, but lots of interference and threats from the Dr. over them- Yes. Threats! (nuther story)

Opioids? No thanks. I now know how to use them. But, had to learn the hard way.

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Reply 15 - Posted by: joew9, 3/7/2018 8:58:24 AM     (No. 11564700)

For me, after surgery and another time during an abscessed tooth I got no pain relief from the prescribed opioids. My family got some relief in that I was too drugged up to complain and moan. So from their perception they believed I got relief.
The side effects were so bad that after two days I quit. It took longer to recover from the opioid side effect than from the surgery. And the abscessed tooth had no pain the very instant they drilled into it and relieved the pressure.

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Reply 16 - Posted by: Jethro bo, 3/7/2018 9:02:20 AM     (No. 11564706)

Well, gee weez, another lie from the fake news. The study was specific and it included hip and knee pain from osteoarthritis, not as, this liar ´journalist´ states in the first sentence (designed to mislead from the start0, ´aches in the joints´. Oseteoarthritis is very differnt from aches i the joints. Why is this misleading? Because osteoarthritis is commonly treated (first line therapy) with non opoid drugs. So there is a selection bias in the design of the study that favors non opioid drugs. The other major red flag is this was published in the Journal of the American Medical Association, a well known liberal poltical advocacy group. It publishes significant political studies disguised as ´science´. Back pain is a hard problem to treat and there is little that has ever been shown consistantly effective so this isn´t a valueless study. But the conclusons are skewed and further stuies are needed.

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Reply 17 - Posted by: Madinmaryland, 3/7/2018 9:05:44 AM     (No. 11564711)

I too had a similar response to opioids. Still had pain, but didn´t care. Give me 800mgm ibuprofen any day for pain relief

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Reply 18 - Posted by: TexaTucky, 3/7/2018 9:56:06 AM     (No. 11564763)

God blessed me with getting really itchy if I take hydrocodone, so I hope I never have any severe pain that can´t be handled by other means.

Since both parents died of overmedication (one accidentally at home, the other negligently by hospital employee), I shun medications anyway, but I believe in the power of appropriately prescribed ones.

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Reply 19 - Posted by: Ribald1, 3/7/2018 10:31:26 AM     (No. 11564814)

A big part of the problem is that people take no personal initiative in learning how to deal with pain anymore.
Pain, emotional and physical, is part and parcel to human life and experience.
There is no need to concern oneself, though as there will come a day when you will feel no more pain. I do not long for that day.

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Reply 20 - Posted by: mildred, 3/7/2018 10:34:50 AM     (No. 11564818)

Why would a doctor prescribe an opioid for a pain level of 3.5-4? At that level the pain is the same as stubbing your toe while wearing heavy boots. When my pain reached about 20 on that scale, I needed everything they had in their power to give relief. Live with stage 4 cancer and then do a study. Tylenol alone does not give any relief to those of us who are really suffering. Doctors also prescribe the opioids because it´s easier for faster results. Then the biggest problem is dealing with the side effects. It´s time that the medical field try alternative pain treatments. Big pharma needs to sell drugs to survive so the patients have to suffer.

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Reply 21 - Posted by: kono, 3/7/2018 10:36:58 AM     (No. 11564820)

The bias is obvious early in the piece, when the words "hard data" are underlined in a tabloid-esque manner not consistent with erudite, professional reporting. Note how many times numbers are included when they support the anti-opioid position, but generalized hand-waving verbiage is employed to tiptoe around contradictory elements.

In addition to the doozie pointed out by #1, it includes qualifiers out the wazoo - "over the long term" being a handy way to dismiss what could be significant short-term differences.

It admits that anxiety was improved more for study participants taking the opioids; but seems uninterested in following that point up.

I´d file this under "The Anatomy of a Hit Piece"...

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Reply 22 - Posted by: earlybird, 3/7/2018 11:12:05 AM     (No. 11564847)

Re #21, that underlined bit is a link to this - not emphasis:

March 6, 2018

Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain
The SPACE Randomized Clinical Trial

Erin E. Krebs, MD, MPH1,2; Amy Gravely, MA1; Sean Nugent, BA1; et al Agnes C. Jensen, MPH1; Beth DeRonne, PharmD1; Elizabeth S. Goldsmith, MD, MS1,3; Kurt Kroenke, MD4,5,6; Matthew J. Bair4,5,6; Siamak Noorbaloochi, PhD1,2
Author Affiliations
JAMA. 2018;319(9):872-882. doi:10.1001/jama.2018.0899

https://jamanetwork.com/journals/jama/article-abstract/2673971?redirect=true

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Reply 23 - Posted by: agrunt, 3/7/2018 12:45:41 PM     (No. 11564918)

Why would a doctor prescribe an opioid for a pain level of 3.5-4?
I have long term pain. I use pain meds to get down to the 4 level. Further all of this numeric level of pain stuff is subjective, My feeling of a level 4 may be the next guy´s 5. No dishonesty here just how you measure the subjective level of pain in your body. I just do not understand how they an use this "number system" to go between differing folks.

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Reply 24 - Posted by: Chuzzles, 3/7/2018 2:29:28 PM     (No. 11565013)

I have been reading Lucianne´s site since the early days of the Clinton presidency and the blue dress. I know how many very intelligent and diverse people comment here from all professions and walks of life.

I have long considered the commenters on this site to be much more informed about any subject than any media writer out there.

I suspect this article is meant to play into the hands of the Feds and their war on opioids. They just cannot leave Doctors alone. Lawyers should get their own medical licenses and stay out of the medical profession. They have no idea how much harm they are doing to law abiding citizens.

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Reply 25 - Posted by: Rumblehog, 3/7/2018 3:10:47 PM     (No. 11565026)

I suspect very much as #24 states.

I´ve had more than 6 back surgeries, and even had an electronic stimulator implanted into my spine to offset nerve damage pain to no avail. The only thing that helps me deal with chronic pain are two VERY expensive medications, one of which is categorized as "opioid-like." Most of my surgeries were straightforward and I never even took the post-surgery pain meds. One major back surgery however, was extremely debilitating and the only way to make it through the recovery period (3 months) was with moderate levels of Hydrocodone. Trust me, this article is B.S.

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Reply 26 - Posted by: toodles3956, 3/7/2018 3:21:28 PM     (No. 11565035)

Lets give the author of this piece a double knee replacement, then ask her if Tylenol works for her.

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Reply 27 - Posted by: GardenGal, 3/7/2018 3:29:32 PM     (No. 11565041)

I live with pain every day of my life. I, along with everyone else on coumadin, cannot take NSAIDS (aspirin, ibuprofen, etc). Tylenol is useless as a pain reliever for me since it never helped at all with any sort of pain. So I use Voltaren ointment (on some joints I am able to), lidocaine cream, and Norco 5/325 or even 2.5/175 often. I am not the problem Opiod user and these studies are idiotic. I have RA, not OA, and many other problems that are painful. I do not medicate for 3 or 4. That is my every day normal and what I try to aim for if my pain gets worse. But when I broke a rib, the only thing that helped was the Norco.

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Reply 28 - Posted by: Doctorfixit, 3/7/2018 4:53:29 PM     (No. 11565104)

One of the more dishonest pieces of propaganda I´ve seen lately. Why is the corporate propaganda machine pushing this hysteria so hard?

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Reply 29 - Posted by: msjena, 3/7/2018 6:05:59 PM     (No. 11565137)

Hydrocodone(Vicodin,etc.) has the advantage of causing drowsiness, which helps the patient tolerate pain after surgery (by falling asleep). Some surgery causes little pain and some a lot. It all depends. I certainly don´t think opiods are necessary for everyday pain, like headaches. But I remember when I had a shoulder injury, the pain was so great that Vicodin didn´t work. The doctor gave me Tramadol,a different narcotic, which helped. People shouldn´t have to suffer if pain relief is available.

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Reply 30 - Posted by: skedaddle, 3/7/2018 6:41:52 PM     (No. 11565162)

Dear Lord, this war on opiates (war on American public suffering pain) is really making me mad and scared.

I was just diagnosed with a Stage 4 cancer. Will I be left to writhe in pain if treatment fails? It seems like the "doctors" who did this study and most of our elected officials would be just fine with me suffering any level of pain when perfectly good medicines exist to relieve suffering.

I´ve recently been given fentanyl three times for quick pain relief during surgical procedures that didn´t require full anesthesia. It worked and I came out of it quickly - the nurses said that´s why they like to use it. I´ve also had Tylenol with codeine for torn ligaments, a broken bone and root canal in the past.

After all that, I´ve never once been tempted to drive down to the bad part of town to buy heroin. That´s because I´m not a drug addict and my doctors were careful with their instructions and quantity prescribed. Opioids works for me. They made my dad see spiders on the walls and you wouldn´t believe how hard it was to get doctors to give alternate pain meds during recovery from joint replacement surgeries.

There´s a lot of blame to go around for people dying from opiates but our government is punishing the innocent and leaving the guilty to go about their business as usual.

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Reply 31 - Posted by: kono, 3/7/2018 7:06:01 PM     (No. 11565178)

I´m grateful for #22´s info. I was not inclined to click, since the underlined text was not colored like a link on the page I read.

That it wasn´t the only element of apparent bias in the article inclines me to stand by the ´hit piece´ characterization, though.

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Reply 32 - Posted by: peeps, 3/7/2018 8:22:42 PM     (No. 11565217)

Agree with #30. After cancer meds, radiation, and surgery, in my case the Hydrocodone helped me relax and heal better without pain. A body without pain and stress is a body that can focus on healing. This may not work in everyone´s case, but I bless the manufacturers of this drug that helped me heal. Not a drug addict.

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Daily Mail [UK], by Jessica Green    Original Article
Posted By: Attercliffe- 7/15/2018 6:19:07 AM     Post Reply
Prince Charles and Prince William reportedly ‘snubbed’ the US President during his visit to Britain - leaving the Queen to meet Donald Trump alone at Windsor Castle. The royal father and son apparently shared their desire to not take part in the arrangements during informal discussions regarding the president’s four-day tour. Trump’s trip was not a state visit and so only the Queen greeted the president and his wife Melania. However even on working trips dignitaries expect to see more members of the royal family than only the Queen. When deciding which royals to include in the meeting, senior courtiers shared concerns about

Maxine Waters: It Is Very Clear That
Trump Is ‘Jealous of Obama’

48 replie(s)
Breitbart Video, by Pam Key    Original Article
Posted By: JoniTx- 7/15/2018 1:10:27 PM     Post Reply
Saturday on MSNBC, Rep. Maxine Waters (D-CA) said President Donald Trump criticizes former President Barack Obama because “he’s jealous of Obama and his administration.” When asked about Trump tweeting that President Obama should have done more about Russian’s interfering in our elections, Waters said, “First of all, let me say this: If the president wrote out at some point and said the sky is falling and it is Obama’s fault, and everybody knows he likes to blame Obama for any and everything that he can come up with. And in addition to that, it is very clear that he’s jealous

Strzok Says FBI Agents Are Permitted
to Engage in Some Adulteries

38 replie(s)
Cybercast News Service, by Staff    Original Article
Posted By: JoniTx- 7/14/2018 3:03:52 PM     Post Reply
FBI Agent Peter Strzok, who worked on the Hillary Clinton email investigation and the investigation of possible ties between Russia and the Trump campaign testified under oath in a congressional hearing on Thursday that FBI agents can engage in some types of adultery. Strzok was asked “what action” he would take if he found out one of his subordinates was conducting an “extramarital affair.” “It depends,” said Strzok. “If it was against the FBI’s regulation in terms of if it was somebody in their chain of command, above or below them, which is inappropriate or not allowed by regulation, I would

Meghan Markle is faking her
smile, says her father

38 replie(s)
Page Six, by Tamar Lapin    Original Article
Posted By: earlybird- 7/15/2018 11:45:23 AM     Post Reply
Meghan Markle‘s smile is hiding fear, stress and the pressure of adjusting to her new royal duties, her father said in an interview published Sunday. “I think she is terrified,” Thomas Markle told The Sun. “I see it in her eyes, I see it in her face and I see it in her smile.” “I’ve seen her smile for years. I know her smile. I don’t like the one I’m seeing now,” he added. “This is a pained smile.”The newly-minted Duchess of Sussex, 36, is struggling to cope with the transition from TV actress to a member of the royal

Russian Hackers Kept DNC Backdoor
Longer Than Anyone Knew

36 replie(s)
Daily Beast, by Kevin Poulsen    Original Article
Posted By: Pluperfect- 7/14/2018 5:04:50 AM     Post Reply
The indictment Friday of 12 Russian military officers for the election hacks against the DNC and Hillary Clinton’s campaign lends a surprising new detail to the 2016 election interference timeline: The Kremlin’s hackers apparently still maintained a foothold in the DNC’s network four months after the Democrats announced that they’d locked the intruders out. Until today, the story of the DNC hack ended promptly on June 14, 2016, when the Democrats went public with the intrusion in the pages of the Washington Post, and Crowdstrike, the security firm hired to respond to the breach, published a detailed technical account. Today’s indictment confirms

‘Art of the Deal’ co-author says
Trump is losing his mind

36 replie(s)
New York Post, by Nikki Schwab    Original Article
Posted By: AltaD- 7/15/2018 7:45:16 PM     Post Reply
The man who co-wrote “The Art of the Deal” said Sunday he believes President Trump’s faculties are diminishing — and that he feels obligated to sound the alarm. “We are in a true emergency,” Tony Schwartz said on CNN Sunday. “And the accelerated rate at which his breakdown or decompensation is occurring is cause for us, and certainly for me, to come on to TV more often, to tweet more often.” Schwartz told CNN’s Brian Stelter that he felt comfortable making that assessment because he had “spent an enormous time with [Trump] over a period of 18 months.”(snip)Stelter pointed out that Schwartz

Recycling: Another environmental
scam goes bust

34 replie(s)
American Thinker, by Colin Flaherty    Original Article
Posted By: magnante- 7/14/2018 6:36:41 AM     Post Reply
Anyone who has ever been to a recycling plant is invariably surprised at how dirty and nasty America’s favorite green activity really is. Trucks dump the material on a long conveyor belt, where a few dozen people pick through by hand what is supposed to be recyclable material, but more and more often is just plain old dirty trash. The recyclables used to be worth something more than bragging rights about liberal moral superiority. Plastic bottles, newspapers, and cardboard, were just a few of the favorites you could ship to China by the ton and make a few bucks along the

McDonald´s, tossed salad, and toilet paper
28 replie(s)
American Thinker, by Jeannie DeAngelis    Original Article
Posted By: JoniTx- 7/14/2018 7:25:36 AM     Post Reply
Americans are encouraged to embrace diversity and be culturally sensitive to those who have flouted our laws and invaded our nation. Meanwhile, illegal aliens arriving in America have no such requirement. Instead, trespassing tribes relocate, and when they do, rather than assimilate, they transfer habits and activities indigenous to the countries from whence they migrated. Thus, Americans suffer from illnesses that are easily traceable to third-world bathroom habits (TWBH) and lack of hygiene in the developing world. It´s not news that illegals work in restaurants as food-handlers. These restaurant workers migrate from

Peter Strzok’s arrogance is
the product of a corrupt FBI

28 replie(s)
New York Post, by Michael Goodwin    Original Article
Posted By: Pluperfect- 7/15/2018 5:04:59 AM     Post Reply
Watching FBI agent Peter Strzok battle with Congress, my initial reaction was pure anger. His repeated, arrogant insistence that he had done nothing wrong despite tons of evidence to the contrary convinced me he deserved immediate firing — if not the firing squad. Gradually, though, anger gave way to amazement as Strzok grew increasingly combative and condescending. Given his predicament, the sneering and smirking were stupid, and yet he persisted. Who is this jerk, I wondered, and how in the hell did he get to be a big shot at the FBI? And why are taxpayers still paying for the privilege of

Left-Wing Antifa Terrorists ‘Freaking
Out’ over Proposed ‘Unmasking’ Law

27 replie(s)
Breitbart Big Government, by John Nolte    Original Article
Posted By: earlybird- 7/14/2018 7:00:28 AM     Post Reply
The left-wing terrorist organization that calls itself Antifa is “freaking out” over a proposed law that would enhance penalties for anyone who “injures, oppresses, threatens, or intimidates any person” while wearing a disguise or mask. Throughout our country, and for a number of years now — and primarily because the establishment media fantasizes about, promotes, enflames and approves of the violence committed against the right (naturally, HuffPo opposes the unmasking law) — Antifa has been allowed to run rampant, committing countless acts of violence against everyday, peaceful supporters of President Donald Trump.

White House Correspondents’ Association
rushes to Jim Acosta’s defense

27 replie(s)
Daily Caller, by Joe Simonson    Original Article
Posted By: JoniTx- 7/14/2018 7:29:11 AM     Post Reply
The White House Correspondents’ Association released a statement defending CNN from President Donald Trump’s refusal to take a question from the network on Friday. “In response to the President lashing out at NBC, CNN and The Sun: Asking smart, tough questions, whether in a presidential press conference or interview, is central to the role a free press plays in a healthy republic,” said WHCA president Margaret Talev. “Given that the president took a question from a CNN reporter in his NATO news conference just a day earlier, maybe he was letting off steam today rather than expressing an official stance

Drug traffickers ´BEHEADED a special
needs girl, 13, in Alabama because she
saw them stab her grandma to death over
her links to El Chapo´s Sinaloa Cartel´

25 replie(s)
Daily Mail [UK] and Associated Press, by Keith Griffith and Staff    Original Article
Posted By: Ribicon- 7/14/2018 11:11:14 PM     Post Reply
A 13-year-old girl in Alabama was beheaded because she saw her Sinaloa Cartel-associated granny stabbed to death by drug traffickers, authorities have said. Mariah Lopez, 13, and her grandmother Oralia Mendoza, 49, were killed on June 4 in Moon Cemetery outside of Huntsville, Alabama, prosecutors revealed in court on Thursday. The new details in the case came in a hearing for 26-year-old Yoni Aguilar, who along with 34-year-old Israel Palomino is charged with two counts each of capital murder in the slayings. At the hearing, investigators testified that the grandmother Mendoza had ties to the Sinaloa Cartel,


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